The proportion of infections which contained all three dhfr mutations whether mixed or not, was 85.6% (137/160, 95%CI 79.2–90.7); the proportion containing double mutant dhps (437, 540) was 10.4% (14/135, 95%CI 5.8–16.8); and the proportion containing all five was 9.6% (13/135, 95%CI 5.2–15.9) (Table 4). This evidence concerns the gene DHFR and infection.