Thus, dRTA can occur following mutation in the SLC4A1gene for the AE1 in autosomal dominant dRTA [82, 83], in the gene ATP6V1B1 coding for β subunit of the vacuolar H+-ATPase (located in chromosome 2p13) in autosomal recessive dRTA with sensorineural deafness [84, 85], and in the gene ATP6VoA4 (located on chromosome 7q33-34) for α subunit of the vacuolar H+-ATPase in autosomal recessive dRTA without sensorineural deafness [86]. The gene discussed is SLC4A1; the disease is distal renal tubular acidosis.