TNF and asthma: Among cases without smoking parents in the home, the TNF-308A allele and TNF-238A alleles showed increased risk of asthma (RR = 2.06; 95% CI, 1.19–3.55; p = 0.0097; false discovery rate = 0.04 for TNF-308A; RR = 2.21; 95% CI, 1.14–4.30; p = 0.019; false discovery rate = 0.04 for TNF-238A) (Table 3).