TRIM21 and neonatal lupus erythematosus: In neonatal lupus erythematosus (NLE), autoantibodies against ribonucleoproteins 48-kDa SSB/La, 52-kDa SSA/Ro (Ro52) and 60-kDa SSA/Ro (Ro60) have received more attention, since they have been shown to be strongly associated with autoimmune responses involved in symptoms like CHB [11].