Following analysis on the two sub groups of CRI patients, one with and the other without proliferative retinopathy (PR), a compound group of genotypes 'GA and AA' of SNP G>A -800 in TGFβ1 gene was found to confer predisposition (P = 0.035; OR: 3.028; CI: 1.079–8.50) only in those CRI patients with proliferative retinopathy (Table 3). Here, TGFB1 is linked to retinal disorder.