BRCA1 and cancer: To summarize the literature on gynaecological screening of BRCA1/2 carriers, including overlap with the present study, eight interval cancers among 24 cancers were diagnosed among a total of 807 BRCA1/2 carriers (Table 1) (Laframboise et al, 2002; Liede et al, 2002; Scheuer et al, 2002; Fries et al, 2004; Kauff et al, 2005; Meeuwissen et al, 2005; Vasen et al, 2005; Gaarenstroom et al, 2006; Oei et al, 2006).