TP53 and neoplasm: Multivariate subgroup analysis including only subjects with BSI high tumours (n=111) and considering factors as covariates potentially to be correlated with disease recurrence and/or mortality like p53 status, pT category, pN category and treatment arm yielded p53 immunopositivity as the only independent marker for improved DFS (P=0.03), whereas it marginally failed to prove to be of significance in terms of OS (P=0.08).