Patients with BSI high/p53− tumours in comparison to patients with BSI high/p53+ lesions had an improved 5-year DFS (P=0.03) (Figure 2B; Kaplan–Meier curves for DFS) and a marginally improved 5-year OS (P=0.07) (Figure 3B; Kaplan–Meier curves for OS), whereas no such difference was noted among cases with BSI low/p53− or + tumours (Table 3). Here, TP53 is linked to neoplasm.