CRP and rheumatoid arthritis: Although no direct indicator of inflammatory disease, such as CRP, persisted in the multivariate model, our study was limited in its ability to discern the influence of inflammation on CV events because we examined only RA patients and not matched non-RA controls and inflammatory markers and radiographs were examined at only a single time point, which occurred at variable times after commencing a variety of antirheumatic drugs rather than at baseline.