Lesions classified as AIM or metaplasia with atypia (n = 20) at our institutions could be reclassified as chronic cervicitis with immature metaplasia (7/20) based on CK17 positivity and p16 negativity and into CIN III (10/20) based on p16 positivity and CK17 negativity. Here, KRT17 is linked to cervical squamous intraepithelial neoplasia.