The prevalence of cell survival over cell proliferationwas confirmed by the increase of Bcl-2 or Bcl-XL, bothantiapoptotic proteins, in cancer versus mucosa specimens, and bythe decrease of PPARα (Figure 1(b)).PPARα was decreased in 21 patients, Bcl-2 was increased in13 patients, and Bcl-XL was increased in 18patients of 24 patients. The gene discussed is PPARA; the disease is cancer.