Other genes involved in chronic inflammation, such asTNFR2 (type-2 TNF receptor) gene [188], IL-6 [189, 199], IL-6 signal transducer gp130 [190], IL-6 receptor [190] genes have alsobeen investigated as a candidate gene for pathogenesis of PCOS.The results of these candidate gene studies and those discussedabove are summarized in Table 2. Here, IL6 is linked to polycystic ovary syndrome.