CYP19A1 and neoplasm: In addition, we have identified VN/14-1 as a highly potent suppressor of growth of human MCF-7 and MCF-7Ca tumour xenograft (derived from MCF7Ca cells, that is human MCF-7 human breast cancer cells stably transfected with human aromatase gene) in female nude mouse model that is more effective than either ATRA or 4-HPR.