PPARG and multiple sclerosis: For instance, PPARγ expression was shown to be reduced in atherosclerotic tissues [21], in epithelial cells from patients with ulcerative colitis [22], in peripheral blood mononuclear cells from patients with multiple sclerosis [23], in alveolar macrophages from patients with allergic asthma [24], and in nasal polyposis from patients with allergic rhinitis [25].