ESR1 and acute myeloid leukemia: Similarly, the compact subepithelial cellular stroma showed strong and diffuse nuclear labeling for estrogen receptor (ER) (Figure 2C) and progesterone receptor (PR) (Figure 2D), along with strong and diffuse cytoplasmic labeling for CD10 (Figure 3A), but labeling for ER (Figure 2C), PR (Figure 2D), and CD10 (Figure 3A) were patchy in the exterior muscle-predominant AML component.