For instance, a study conducted primarily in a sample of patients with statin-induced myopathy ascertained through neurology clinics indicated that up to 10% of statin-intolerant subjects were heterozygous or homozygous for disease-causing mutations in rare metabolic myopathies, namely carnitine palmitoyl transferase II deficiency and McArdle disease [7]. The gene discussed is CPT2; the disease is hyperinsulinemic hypoglycemia, familial, 4.