Several research groups (including us) have demonstrated by immunohistochemical technique a manifold increase of the p16ink4a expression in cervical dysplasia and carcinomas in comparison with that in normal epithelium [16-19] There is an abundant evidence demonstrating that immunohisto-/cytochemical detection of the protein p16ink4a is a promising test for revealing the HPV-infected cells with malignant potential [[10,20], for review see [21]]. This evidence concerns the gene CDKN2A and carcinoma.