Tumours larger than 1.5 cm had a significantly higher level of VEGF-C expression (P=0.023) but unlike VEGF-A, no association was found in relation to the tumour grade (P=0.214) or with the hormonal receptor status (P=0.865 for ER and P=0.624 for PR). The gene discussed is NR4A1; the disease is neoplasm.