Since Stat3 phosphorylation at Tyr705 is elevated in cervical and endometrial cancer tissues and Stat3 pathway has been shown to participate in oncogenesis (Bromberg et al, 1999; Bowman et al, 2000), we examined whether the inhibition of Stat3 pathway by dnStat3 in cervical cancer cells could suppress cancer cell growth. This evidence concerns the gene STAT3 and cervical cancer.