Mutations in ABCA4 have been associated with autosomal recessive STGD (arSTGD) [5], autosomal recessive retinitis pigmentosa (arRP) [6], autosomal recessive cone-rod dystrophy (arCRD) [7] and age-related macular degeneration (AMD) [8]. This evidence concerns the gene ABCA4 and age-related macular degeneration.