Because the glp-4;sek-1 mutant was similarly susceptible to a variety of C. albicans strains as well as to the non-albicans strains Candida krusei and Candida parapsilosis (Figure 1B), because it did not produce progeny, and because we found it compelling to study Candida pathogenesis in immunocompromised nematodes (in some ways analogous to candidiasis in immunocompromised humans), we utilized the glp-4;sek-1 strain in all of the further studies described below. The gene discussed is MAP2K4; the disease is candidiasis.