Specifically, Fcer1a is the Fc fragment of IgE and is involved in the immune response [22]; Tcfec is a transcription factor that induces, among other genes, the G-CSF receptor gene [23,24]; Ptprcap is a transmembrane protein associated with CD45, a key regulator of lymphocytes activation [25]; F2rl3 is a member of G protein-coupled protease-activated receptors (PARs) of the coagulation factor II (thrombin) and plays an important role in platelet activation [26]; Mgmt is a DNA repair enzyme that is frequently lost in cancer due to epigenetic silencing [27]. This evidence concerns the gene IGHE and cancer.