TP53 and neoplasm: When CK5/14 positivity was correlated with clinicopathological characteristics within the ER-negative tumor subgroup, associations with negative lymph node status and positive p53 status were not seen (p = 0.14 and p = 0.65, respectively), but significant association between CK5/14 immunopositivity and negative HER-2 status emerged (p = 0.01, Table 1).