Expressions of HGM, MUC6, MUC2 and CD10 were demonstrated in 33 (63.5%), 35 (67.3%), 31 (59.6%) and 19 (36.5%) cases of the 52 cases of C-Ca with differentiated-type tumours, respectively, and 46 (56.1%), 48 (58.5%), 64 (78.0%) and 23 (28.0%) cases of the 82 cases of D-Ca with differentiated-type tumours, respectively. The gene discussed is MUC6; the disease is neoplasm.