The present study was designed in order to analyze the expression of CXCL12, CXCL8, CXCL1, and HGF in five human uveal melanoma cell lines (92.1, SP6.5, MKT-BR, OCM-1, UW-1) and to investigate the effects of these factors on the migratory ability of the 5 cell lines. The gene discussed is CXCL8; the disease is uveal melanoma.