In contrast to these results, Green and coworkers [12] did not observe any correlation between the cytokines IL-1α, IL-1β, IL-4, IL-6, IL-8, TNF-α, TNF-β, IL-2, IL-5, IL-7 and IFN-γ and tumour histological grade, patient age or lymph node metastasis in breast cancer patients, but that study analyzed only RNA levels. Here, TNF is linked to metastatic malignant neoplasm in the lymph nodes.