These latter oligosaccharides govern interactions of α-dystroglycan with extracellular matrix proteins [25,26], and their deficiency is responsible for several congenital muscular dystrophies, including Walker-Warburg syndrome, Muscle-Eye-Brain disease, and Fukuyama's muscular dystrophy [27-29]. This evidence concerns the gene DAG1 and muscular dystrophy-dystroglycanopathy, type A.