The endothelium represents the first-line contact, where the accumulation of oxLDL induces the expression of adhesion molecules (e.g., VCAM-1) and proinflammatory cytokines/chemokines (e.g., MCP-1, see also Table 1) critically involved in the initiation and perpetuation of arteriosclerosis, making them potential therapeutic targets [4]. This evidence concerns the gene CCL2 and arteriosclerosis.