A significant stimulatory effect of SCH immunization on splenic, lymph node and thymic CD4+ cell number was found (F1,36 = 11.6, p = 0.0016; F1,36 = 27.1, p < 0.001 and F1,36 = 18.8, p < 0.001, respectively, Fig. 3 to 5). This evidence concerns the gene CD4 and spindle cell hemangioma.