For Kaplan–Meier plots with patients with malignant tumours, the parameters were dichotomised in two groups, one with low (1) HER2/neu or cytoplasmic CXCR4 expression or SDF-1 abundance and one with medium or high (2/3) expression/abundance of the corresponding protein (Figure 3). This evidence concerns the gene CXCR4 and neoplasm.