Most strikingly, 12 kallikreins (KLK2, KLK3, KLK4, KLK5, KLK6, KLK7, KLK8, KLK10, KLK11, KLK13, KLK14, and KLK15) are concurrently upregulated in ovarian cancer (Borgono and Diamandis, 2004). Here, KLK4 is linked to ovarian carcinoma.