The structures of the J-domain from six Hsp40 and Hsp40-like proteins have been published: E. coli DnaJ (Huang, Flanagan, & Prestegard, 1998; Pellecchia, Szyperski, Wall, Georgopoulos, & Wüthrich, 1996); human HDJ1 (Qian, Patel, Hartl, & McColl, 1996); E. coli Hsc20 (Cupp-Vickery & Vickery, 2000); the large T antigen from murine polyomavirus (Berjanskii et al., 2000); the large T antigen from SV40 in conjunction with the retinoblastoma tumour suppressor (Kim, Ahn, & Cho, 2001); and bovine auxilin (Gruschus, Greene, Eisenberg, & Ferretti, 2004; Jiang et al., 2003). Here, DNAJB1 is linked to neoplasm.