In the malignant tumours (Spearman: P = 0.024), but not in the benign lesions (Spearman: P = 0.46) or in the normal mammary gland (Spearman: P = 0.62), the VEGF-C score index had higher and significant values in the intratumoral (intramammary) than in extratumoral (extramammary) fields (figure 5). This evidence concerns the gene VEGFC and neoplasm.