Both numbers of lymphatics with or without VEGFR-3 expression in NMG and carcinomas had higher significant values in extramammary/extratumoral fields compared to intramammary/intratumoral stroma (Spearman test; NMG: P < 0.05 for lymph vessels without and P < 0.01 for those with VEGFR-3 expression; MT: P < 0.05 for lymph vessels without, and P < 0.01 for those with VEGFR-3 expression), whereas in adenoma the same result was obtained for lymphatic vessels with VEGFR-3 (Spearman test: P < 0.01). The gene discussed is FLT4; the disease is adenoma.