This study estimated pancreatic cancer risk in BRCA2 carriers by age 70 years to be 2.1% (95% CI 1.2–3.0%) in men, and 1.5% (95% CI 0.9–2.1%) in women, reflecting a combined RR of 3.51 (95% CI 1.87–6.58) (The BCLC, 1999). This evidence concerns the gene BRCA2 and familial pancreatic carcinoma.