In the BCLC-BRCA1 families, there was some evidence of an increased risk of prostate cancer for men younger than 65 years (RR 1.82, 95% CI 1.01–3.29), but not for those aged 65 years or older (RR=0.84, 95% CI 0.53–1.33) (Thompson and Easton, 2002). This evidence concerns the gene BRCA1 and Familial prostate cancer.