Both, PR-A and -B as well as PR-B alone were associated with chemosensitivity to paclitaxel (P=0.007 and P=0.022, respectively), whereby tumours with relatively high levels of receptor expression appeared less sensitive to paclitaxel compared with carcinomas with low levels of the PR (Figure 3A and B). The gene discussed is S100A6; the disease is carcinoma.