Among these transcripts exhibiting both cancer-associated nsSNPs and cancer-associated UTR-SNPs (highlighted in light grey in Additional file 1) are those encoding Heat shock cognate 71 kDa protein, polyadenylate binding protein (PABP)-3, translationally controlled tumour protein (TCTP), immunoglobulin gamma FcRIIIA, and dynein light chain 1 (DNCL1, see Table 2). The gene discussed is HSPA8; the disease is cancer.