Our list of cancer-associated variants contains a number of genes possibly involved in the cellular capabilities that might be acquired by cancer cells [28], e.g., translationally controlled tumour protein TCTP, IL-4-R, HLA class II antigens, TIMP-3, CD147, CD44, and the jun-B, c-fos, AF4, Ki-Ras and RAF proto-oncogenes. The gene discussed is CD44; the disease is cancer.