BRD7 and nasopharyngeal carcinoma: Overexpression of BRD7 could inhibit NPC cell growth and arrest cells in cell cycle by transcriptionally regulating some important molecules involved in ras/MEK/ERK and Rb/E2F pathway, and downregulate the promoter activity of E2F3. The nuclear localization of BRD7 was critical for the expression of cell cycle related molecules and cell biological function [27].