MTHFR and coronary artery disorder: Thus, our null finding for MTHFR genotypes and mortality is not at all surprising, and in line with the reports from Anderson (mortality in MTHFR 677TT versus677CC subjects = 11.7% versus 15.1%, P = 0.62) [17], and from others who observed divergent associations with incident CAD when considering tHcy or the MTHFR 677C→T polymorphism [23].