Importantly, we showed also that self-renewing and multipotent CSC isolated from fresh samples of ependymoma are: bipolar RG-like cells; express the CD133+/Nestin+/RC2+/brain lipid-binding protein (BLBP)+ immunophenotype of RG; and are both required and sufficient to generate tumours in vivo. Here, FABP7 is linked to neoplasm.