In addition, RET/PTC is more prevalent in childhood thyroid cancers, whereas BRAF V600E mutations are extremely rare in children and the age of patients with PTCs who express BRAF V600E is more than that of the general PTC population (Xing et al, 2005; Ciampi and Nikiforov, 2006). Here, BRAF is linked to thyroid gland carcinoma.