From our analysis of BCC compared to normal skin tissue, while we found no significant changes in shh expression levels, we report an approximately 11 fold increased expression of PTCH1 [expression values 25.65 vs. 271.62], and also increased expression of gli2 (7.39 fold; P = 0.00009) [expression values 23.52 vs. 173.73], respectively. This evidence concerns the gene PTCH1 and skin basal cell carcinoma.