VEGFA and neoplasm: The vascular endothelial growth factor (VEGF) gene family, which encodes five polypeptide growth factors, VEGF-A, -B, -C, -D, and -E, is particularly important because of its angiogenic and lymphangiogenic properties that promote the growth and metastasis of neoplasms (Ferrara and Davis-Smyth, 1997).