In fact, when the intrinsic subtype of each of the patients in Figure 4 was determined by clustering all 95 tumor samples using the intrinsic list of Sorlie et al. [12], a statistically significant association between p53 status and tumor subtype was observed (p = 0.002), with 31% of luminal tumors and 80% of basal-like tumors having mutant p53. This evidence concerns the gene TP53 and neoplasm.