Further evaluation of this data showed that, in the whole sample, Glu27 homozygotes (Glu27Glu27) of ADRB2-27 had a lower frequency of diabetes (Odds Ratio (OR) 0.56, 95% Confidence Interval (CI) 0.36 – 0.91) when compared with Gln27 carriers (Gln27Glu27 or Gln27Gln27). Here, ADRB2 is linked to diabetes mellitus.