MYC and benign prostatic hyperplasia: Royuela et al (2000) described MYC immunostaining to be positive in prostate tumours and BPH (Jenkins et al, 1997; Royuela et al, 2000), which is in concordance with our observations. The second study indicated that cytoplasmic immunostaining of MYC increased with copy number gains of chromosome 8, which in turn correlated with the occurrence of lymph node metastases (Jenkins et al, 1997).