Finally, in human hepatocellular carcinoma, a similar discrepancy between c-myc gene amplification and immunostaining was reported as in the present study: despite a c-myc amplification, human hepatocellular carcinoma had less nuclear and cytoplasmic MYC imunostaining than noncancerous livers without c-myc amplification (Chan et al, 2004). Here, MYC is linked to hepatocellular carcinoma.