Although PCA of B-precursor ALL cases yielded distinct clusters for Pro-B-ALL, c-ALL/Pre-B-ALL, and mature B-ALL, the precursor subtypes c-ALL/Pre-B-ALL with t(9;22)/BCR-ABL were not completely discriminated from those without t(9;22)/BCR-ABL. Here, ABL1 is linked to acute lymphoblastic leukemia.