In the above-mentioned study, Yeoh et al (2002) discriminated 327 childhood ALL cases in the following subtypes: T-ALL, E2A-PBX1/t(i;19), BCR-ABL/t(9;22), TEL-AML1/t(12;21), MLL/11q23 rearrangements, and hyperdiploid karyotype. Here, RUNX1 is linked to acute lymphoblastic leukemia.