PRF1 and neoplasm: An insight into the mechanisms of the observed adjuvant effect of γ-inulin is revealed by the flow cytometry-based detection at the treated tumour site of cytotoxic T cells that have lysosomal-associated membrane protein-1 (LAMP-1, CD107a antigen) detectable on their surface (CD8+CD107a+), which occurs when these cells undergo degranulation (releasing granzyme B and perforin) upon their contact with specific target cells (Burkett et al, 2005).