LRRK2 and Lewy body dementia: Purified cortical LBs, biochemically isolated from DLB brains [15], were positive for staining by both anti-α-synuclein (Figure 4F) and anti-LRRK2 Ab4 (Figure 4E), whereas omitting the primary antibody revealed no labeling of the purified cortical LBs (Figure 4G).