RAP2A and lung carcinoma: This region includes the genes SLITRK6, SLITRK5, GPC5, GPC6, DCT, TGDS, SOX21, ABCC4, CLDN10, DZIP1, DNAJC3, UGCGL2, HS6ST3, HSP90AB6P, OXGR1, MBNL2 and RAP2A. In addition, this region also encompasses the micro RNA cluster miR-17-92, which is reported to induce tumour cell growth and to be overexpressed and sometimes amplified in aggressive forms of lung cancer (Hayashita et al, 2005).