We found an upregulation of E2F1 in all tumour types which is consistent with others studies (Saiz et al, 2002; Onda et al, 2004), and we observed a link between E2F1 and p14ARF expression in nontumoral thyroid tissue as well as in follicular adenomas and carcinomas. The gene discussed is E2F1; the disease is follicular thyroid adenoma.