Indeed, such a relationship was observed between p14ARF and E2F1 expression in normal (r=0.41, P=0.01) and tumour tissues (r=0.64 to 1, P<0.05) except for papillary carcinomas (r=0.04, P=0.86) (Table 4). Here, E2F1 is linked to thyroid gland papillary carcinoma.