Furthermore they suggest that overall CEA-TPA-CA15.3 panel is more suitable than MCA-CA15.3 association for an intensive post-operative follow-up of breast cancer patients with tumour markers and that an intensive post-operative follow-up with CEA-TPA-CA15.3 panel can early detect relapsing patients with more favourable prognosis. The gene discussed is PLAT; the disease is breast cancer.